Association between Polymorphisms of Antioxidant Gene (MnSOD, CAT, and GPx1) and Risk of Coronary Artery Disease

Table 3

Association between MnSOD, CAT, and GPx1 genotypes and risk of coronary artery disease severity.

Genotype	CAD severity
	0	1	2	3
MnSOD
Val/Val	181	119	102	131
Val/Ala+Ala/Ala	29	40	27	28
OR(95% CI)^a	1.00	2.31(1.32-4.03)	1.92(1.02-3.61)	1.40(0.75-2.61)
P-value		0.003	0.043	0.288
CAT
C/C	197	145	117	141
C/T+T/T	13	14	12	18
OR(95% CI)^a	1.00	1.25(0.55-2.83)	1.40(0.58-3.34)	1.80(0.82-3.99)
P-value		0.592	0.454	0.146
GPx1
Pro/Pro	191	142	120	144
Pro/Leu	19	17	9	15
OR(95% CI)^a	1.00	1.24(0.60-2.59)	0.83(0.34-2.03)	1.05(0.49-2.28)
P-value		0.562	0.689	0.895

a: adjusted for age, sex, cigarette smoking, and alcohol drinking.