Excess Hydrocortisone Hampers Placental Nutrient Uptake Disrupting Cellular Metabolism

Figure 2

Hydrocortisone’s effects in placental explants’ lipid metabolism. (a) Fatty acid oxidation, in nmol/hour/mg of protein, was inhibited by glucocorticoids in a dose dependent manner. (b) Fatty acid esterification, in pmol/hour/mg of protein, was also decreased in a dose dependent manner. Values are represented as means ± SEM for at least 5 independent experiments, in triplicate. p≤0.05; p≤0.01; p≤0.001 relative to control.

(a)

(b)