miR-144-5p Enhances the Radiosensitivity of Non-Small-Cell Lung Cancer Cells via Targeting ATF2

Figure 1

miR-144-5p expression in lung cancer patient samples and cell lines treated with irradiation. (a) Relative expression levels of miR-144-5p in normal lung tissue and lung cancer specimens were measured by real-time polymerase chain reaction. NLT, normal lung tissue ; AC, adenocarcinoma ; SC, squamous carcinoma ; SCLC, small cell lung cancer . versus NLT, ^# versus SCLC. (b) miR-144-5p expression in the indicated NSCLC cell lines. Data are representative images or expressed as the mean ± standard deviation of each group of cells from three separate experiments. versus 16-HBE, versus 16-HBE, versus H1417. (c) miR-144-5p expression in A549 cells and (d) H460 cells after radiation treatment at different doses (0 Gy, 2 Gy, 4 Gy, and 8 Gy). versus 0 Gy.

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