Blockade of RBP-J-Mediated Notch Signaling Pathway Exacerbates Cardiac Remodeling after Infarction by Increasing Apoptosis in Mice

Table 1

The cardiac function at day 0 and day 28 following MI.

	Day 0		Day 28
	Myh6-RBP- mice	RBP-- mice	Myh6-RBP--MI mice	RBP--MI mice	Myh6-RBP--sham mice	RBP--sham mice
LVEF%
FS%
LVVol s
LVVol d

At day 0, there was no significant difference between Myh6-RBP- mice and RBP- mice in cardiac function. At day 28, LVEF and FS were smaller, while LV Vol s was greater in Myh6-RBP--MI mice compared with RBP--MI mice. And there was no significant difference between Myh6-RBP--MI mice and RBP--MI mice in LV Vol d. Data are shown as mean±SD. for RBP- mice with sham operation, 6 for Myh6-RBP- mice with sham operation, 12 for RBP- with MI, and 12 for Myh6-RBP- mice with MI. versus RBP- with MI in LV Vol s. And versus RBP- with MI in LVEF and FS by Student’s t-test.