A Randomized, Double Blind, Placebo Controlled, Parallel-Group Study to Evaluate the Safety and Efficacy of Curene® versus Placebo in Reducing Symptoms of Knee OA
Table 9
Laboratory parameters (ITT population).
Index
OLNP-08 500 mg
Placebo
N=25
N=25
Baseline visit
Visit 5
Mean change
Baseline visit
Visit 5
Mean change
Haemoglobin
13.81±1.38
14.67±0.95
0.87±0.91
13.62±1.02
14.67±0.65
-1.02±0.86
Platelet count
2.19±0.60
2.99±0.66
0.8±0.53
2.43±0.66
3.04±0.53
0.61±0.55
ESR
28.2±4.52
25.12±3.00
3.08±3.12
27.88±4.01
27.68±3.97
0.2±2.31
RBC
5.04±0.58
5.34±0.54
0.30±0.6
4.96±0.52
5.41±0.7
0.45±0.63
WBC
8260±1283.87
8580± 1559.11
320±1360.76
8200±1600.78
8420±1476.76
220±925.11
Random Glucose
142.88±25.67
142.52±18.22
0.36±14.41
141.8±25.22
146.68±18.34
4.88±13.07
S. Creatinine
0.79±0.14
0.79±0.18
0.00±0.17
0.78±0.20
0.92±0.32
0.14±0.30
BUN
32.88±9.00
36.52±6.37
3.64±8.54
35.24±8.00
34.36±8.58
0.88±8.1
Bilirubin
0.75±0.22
0.83±0.15
0.08±0.19
0.72±0.26
0.73±0.24
0.01±0.16
SGOT
31.38±6.38
31.44±5.28
0.06±8.17
29.56±7.88
31.04±5.52
1.48±8.36
SGPT
21.59±8.13
24.56±7.92
2.99±6.5
21.48±6.25
26.04±5.72
4.56±5.35
SAP
112.52±24.38
119.76±18.97
7.24±11.4
116.16±24.47
120.2±20.12
4.04±11.97
S. Sodium
140.16±5.61
138.4±3.57
1.76±5.98
139.5±2.39
137.88±5.92
1.62±5.64
S. Potassium
4.20±0.53
4.28±0.53
0.08±0.66
4.15±0.42
4.57±0.66
0.42±0.67
S. Albumin
4.07±0.41
4.48±0.76
0.41±0.74
4.13±0.54
4.57±0.71
0.44±0.72
Urine PH
6.46±0.66
6.66±0.47
0.2±0.5
6.38±0.39
6.48±0.37
0.1±0.32
Specific gravity
1.01±0.01
1.01±0.00
0.00±0.00
1.01±0.00
1.01±0.00
0.00±0.00
P value < 0.05, values are presented in absolute value. Within the group analysis by pair t-test.
