BioMed Research International / 2018 / Article / Tab 1 / Research Article
Identifying Frail-Related Biomarkers among Community-Dwelling Older Adults in Japan: A Research Example from the Japanese Gerontological Evaluation Study Table 1 Sample characteristics, numbers of participants, and proportions (%) by levels (below normal, normal, and above normal) of study biomarkers according to the SOF Frailty category (
).
SOF Frailty Index category Robust Intermediate Frail ( ) ( ) ( ) Frequency (row%) Demographic Age in year, mean (SD) 70.9 (4.8) 71.7 (5.3) 73.6 (6.4) Gender Men 732 (49.1) 609 (40.8) 151 (10.1) Women 702 (42.9) 671 (41.0) 263 (16.1) Biomarkers (units) HbA1c (%): men Below normal 81 (53.6) 53 (35.1) 17 (11.3) Normal 527 (48.3) 454 (41.7) 109 (10.0) Above normal 121 (48.8) 101 (40.7) 26 (10.5) HbA1c (%): women Below normal 120 (40.4) 131 (44.1) 46 (15.5) Normal 532 (44.8) 482 (40.6) 174 (14.6) Above normal 53 (34.4) 59 (38.3) 42 (27.3) HDL (mg/dL) Below normal 147 (38.3) 174 (45.3) 63 (16.4) Normal 1255 (46.7) 1087 (40.4) 347 (12.9) Above normal 32 (58.2) 19 (34.5) 4 (7.3) LDL (mg/dL) Below normal 25 (45.5) 16 (29.1) 14 (25.5) Normal 1306 (45.7) 1172 (41.1) 377 (13.2) Above normal 103 (47.2) 92 (42.2) 23 (10.6) Triglyceride (mg/dL) Below normal 5 (35.7) 8 (57.1) 1 (7.1) Normal 1023 (46.4) 883 (40.1) 297 (13.5) Above normal 406 (44.6) 389 (42.7) 116 (12.7) Haemoglobin (g/dL) Below normal 259 (38.3) 297 (43.9) 120 (17.8) Normal 1118 (48.0) 935 (40.1) 277 (11.9) Above normal 57 (46.7) 48 (39.3) 17 (13.9) Serum albumin (g/dL) Below normal 89 (36.0) 89 (36.0) 69 (27.9) Normal 1335 (46.8) 1176 (41.2) 341 (12.0) Above normal 10 (34.5) 15 (51.7) 4 (13.8) Creatinine (mg/dL) Below normal 34 (43.6) 34 (43.6) 10 (12.8) Normal 1273 (46.3) 1117 (40.6) 362 (13.2) Above normal 127 (42.6) 129 (43.3) 42 (14.1) Uric acid (mg/dL) Below normal 27 (45.0) 25 (41.7) 8 (13.3) Normal 1252 (46.0) 1120 (41.1) 352 (12.9) Above normal 155 (45.1) 135 (39.2) 54 (15.7) Urine Protein absence 1213 (45.9) 1083 (41.0) 344 (13.0) Protein: trace or positive 221 (45.3) 197 (40.4) 70 (14.3) eGFR (mL/min/1.73 m2 ) Normal 1120 (47.0) 963 (40.4) 300 (12.6) Above normal 314 (42.1) 317 (42.6) 114 (15.3)