CSF-S100B Is a Potential Candidate Biomarker for Neuromyelitis Optica Spectrum Disorders

Figure 3

Correlations between CSF-GFAP and S100B levels in NMOSD, MS, and NMOSD subgroups. In NMOSD patients, the CSF-S100B and GFAP levels were strongly correlated with each other (a). In MS patients, the CSF-S100B levels did not correlate with the GFAP levels (b). Among NMOSD subgroups, the CSF-S100B and GFAP levels strongly correlated with each other in AQP4-Ab-positive NMOSD [AQP4-Ab (+)] patients (c); in seronegative (d) and MOG-Ab-positive NMOSD [MOG-Ab (+)] patients (e), the CSF-S100B levels did not correlate with the GFAP levels. Statistical testing was performed by using Spearman’s rank correlation analysis. r = Spearman’s rho.

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