Identification of Candidate Biomarkers in Malignant Ascites from Patients with Hepatocellular Carcinoma by iTRAQ-Based Quantitative Proteomic Analysis

Figure 4

The differentially distributed protein levels in top ranked pathways. (a) Upregulated proteins in glycolysis/gluconeogenesis pathway. 1.2.1.12, GAPDH; ENO1 (Enolase-1); 2.7.2.3, PGK1 (phosphoglycerate kinase 1). (b) Downregulated proteins in coagulation and complement cascades pathway. C4, CO4B; fibrinogen, FIBA; AT3, ANT3 (antithrombin III); PLG, PLMN (plasminogen); vitronectin, VTNC; α2AP, A2AP; F12, coagulation factor III. The regulated proteins in HCC vs. HD are marked in colored boxes. Red box indicates an upregulated protein; green box indicates a downregulated protein; gray box indicates that no significant difference was observed.

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