Role of Some Natural Antioxidants in the Modulation of Some Proteins Expressions against Sodium Fluoride-Induced Renal Injury

Figure 5

Histological analysis of kidneys’ sections (scale= x400) from (a) normal architecture of control group; (b) NaF-intoxicated group showing damaged and obliterated glomerular corpuscle (black arrow), proximal (yellow arrow), and distal (red arrow) convoluted tubules; (c) and (d) kidneys’ sections from NAC-treated group and THQ-treated group, respectively, showing renal cortex in the form of normal renal corpuscle with normal glomerulus (black arrow), normal pattern of proximal convoluted tubules (red arrow), and few distal convoluted tubules lined with mildly destructed epithelium, mild vacuolization in tubular epithelium (yellow arrow); and (e) kidney section from combined-treated group showing renal cortex in the form of almost normal renal corpuscle with normal glomerulus (black arrow), few proximal convoluted tubules showing destructed epithelial lining, vacuolization in tubular cells focal necrosis, and cell infiltration (red arrow) and distal convoluted tubules lined by a lower, cuboidal epithelium (yellow arrow). (Scale 400.)

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