Role of Some Natural Antioxidants in the Modulation of Some Proteins Expressions against Sodium Fluoride-Induced Renal Injury

Table 1

Serum levels of kidney function parameters, BAX/Bcl-2 ratio, and renal TNF-α in control, NaF, and all treated groups.

Parameters	Control	NaF	THQ	NAC	THQ + NAC
Creatinine (mg/dl)	1.4± 0.21	2.2± 0.16	1.6± 0.082	1.8± 0.068	1.5± 0.19
Urea (mg/dl)	16± 1.2	80± 3.7	36± 1.9	27± 1.8	23± 1.7
Uric Acid (mg/dl)	3.7±0.41	7.3±0.75	6.9±0.75	5.7±1.0	4.5±0.39
BAX/Bcl-2 ratio	100.5±0.34	5065±45.2	1143±37.3	1053±9.23	325.4±20.9
TNF-α (pg/ml)	34.65±1.04	203.8±6.58	87.63±3.54	105.1±1.9	65.26±3.17

Notes. Data are shown as mean ± SEM (N=6). P≤ 0.001 versus control and P≤ 0.001 versus NaF-treated group.