Pathway Network Analysis of Complex Diseases Based on Multiple Biological Networks

Table 5

Top 15 pathways identified with our method in Gastric Cancer Data Set.

Rank	Pathway Name	gene	p-value
1	KEGG_DNA_REPLICATION	36	1.50e-20
2	KEGG_PROTEASOME	48	9.07e-05
3	KEGG_ARGININE_AND_PROLINE_METABOLISM	54	0.000489
4	KEGG_GLYCEROLIPID_METABOLISM	49	5.12e-05
5	KEGG_PURINE_METABOLISM	159	1.68e-12
6	KEGG_PATHWAYS_IN_CANCER	328	2.52e-09
7	KEGG_SPLICEOSOME	128	0.0003348
8	KEGG_NUCLEOTIDE_EXCISION_REPAIR	44	0.0001406
9	KEGG_MELANOGENESIS	102	0.0481885
10	KEGG_RNA_DEGRADATION	59	0.0003626
11	KEGG_MAPK_SIGNALING_PATHWAY	267	0.0014066
12	KEGG_GLYCEROLIPID_METABOLISM	49	5.119e-05
13	KEGG_DRUG_METABOLISM_CYTOCHROME_P450	72	0.0115133
14	KEGG_CYTOKINE_CYTOKINE_RECEPTOR_INTERACTION	267	0.0183417
15	KEGG_PROSTATE_CANCER	89	0.0274642