BioMed Research International

Research Article

Screening of Serum Protein Markers for Avascular Osteonecrosis of Femoral Head Differentially Expressed after Treatment with Yuanshi Shengmai Chenggu Tablets

Table 4

Differentially expressed protein between SANFH-TCM and SANFH.
AccessionDescription valueRatio (mean)
Upregulated protein
Q9NP78ATP-binding cassette sub-family B member 921.82029412
Q86XH1IQ and AAA domain-containing protein 113.86725
P02671Fibrinogen alpha chain13.65918665
P02675Fibrinogen beta chain13.64325401
P02679Fibrinogen gamma chain13.23321597
P01019Angiotensinogen2.391730769
Q68CQ4Digestive organ expansion factor homolog2.26525
P03950Angiogenin2.0039
P35527Keratin, type I cytoskeletal 91.928576923
Q8WXD2Secretogranin-31.91025
P27918Properdin1.763869048
P14618Pyruvate kinase PKM1.632333333
P05154Plasma serine protease inhibitor1.607923077
Q04756Hepatocyte growth factor activator1.590333333
P02775Platelet basic protein1.56775
P02776Platelet factor 41.559232955
P02749Beta-2-glycoprotein 10.00003221.548
Q96KN2Beta-Ala-His dipeptidase0.00001691.533115385
P01023Alpha-2-macroglobulin1.519228916
P06727Apolipoprotein A-IV1.4910721
P06396Gelsolin1.485481481
P01769Ig heavy chain V-III region GA1.45675
P10720Platelet factor 4 variant1.450190476
P05090Apolipoprotein D1.385849624
P19823Inter-alpha-trypsin inhibitor heavy chain H21.376936508
P01871Ig mu chain C region1.37344898
P01616Ig kappa chain V-II region MIL1.35375
P34096Ribonuclease 41.3485
P29122Proprotein convertase subtilisin/kexin type 61.3275
P80108Phosphatidylinositol-glycan-specific phospholipase D1.320666667
P55056Apolipoprotein C-IV1.3169
O95445Apolipoprotein M1.314954545
Q9UHG3Prenylcysteine oxidase 11.305045455
P08603Complement factor H1.296578143
P02787Serotransferrin1.2947
P05164Myeloperoxidase1.282
Q8WWA0Intelectin-11.2735
P29622Kallistatin1.267285714
Q9NP79Immunoglobulin J chain1.260973684
Q86XH2CD5 antigen-like1.248355422
P02671Plasma kallikrein1.236383333
P02675Serum amyloid P-component1.236112319
P02679Inter-alpha-trypsin inhibitor heavy chain H11.230389423
P01019Alpha-actinin-41.23
Downregulated protein
P04217Alpha-1B-glycoprotein0.826346154
P01613Ig kappa chain V-I region Ni0.825583333
Q16610Extracellular matrix protein 10.821529412
Q92954Proteoglycan 40.8145
Q02818Nucleobindin-10.813125
P01742Ig heavy chain V-I region EU0.803428571
P04434Ig kappa chain V-III region VH (Fragment)0.802166667
P55774C-C motif chemokine 180.79825
Q9HDC9Adipocyte plasma membrane-associated protein0.798083333
P01011Alpha-1-antichymotrypsin0.796217391
P01621Ig kappa chain V-III region NG9 (Fragment)0.795
P01717Ig lambda chain V-IV region Hil0.78905
P04196Histidine-rich glycoprotein0.783991667
P04433Ig kappa chain V-III region VG (Fragment)0.783357143
P35542Serum amyloid A-4 protein0.752563218
P0DJI8Serum amyloid A-1 protein0.748036765
P27824Calnexin0.73825
P00740Coagulation factor IX0.733622222
Q9UGM5Fetuin-B0.721833333
P0C0L4Complement C4-A0.71725
Q08380Galectin-3-binding protein0.713721805
P04438Ig heavy chain V-II region SESS0.70425
P20742Pregnancy zone protein0.698695238
P13645Keratin, type I cytoskeletal 100.69635
Q86UD1Out at first protein homolog0.694666667
P02751Fibronectin0.692870958
P04208Ig lambda chain V-I region WAH0.6685
P01861Ig gamma-4 chain C region0.655777778
P18428Lipopolysaccharide-binding protein0.640994118
P49721Proteasome subunit beta type-20.0198097940.6185
P25789Proteasome subunit alpha type-40.609
P01743Ig heavy chain V-I region HG30.607136364
P01620Ig kappa chain V-III region SIE0.5894375
P02452Collagen alpha-1(I) chain0.4901
P02741C-reactive protein0.445641414
P01714Ig lambda chain V-III region SH0.442666667
P0DJI9Serum amyloid A-2 protein0.424595238