Research Article

Screening of Serum Protein Markers for Avascular Osteonecrosis of Femoral Head Differentially Expressed after Treatment with Yuanshi Shengmai Chenggu Tablets

Table 8

Differently enriched pathways were obtained in SANFH-TCM versus SANFH.

Pathway_accPathway_Name valueProtein in backgroundProteins in Diff ExpProtein list

hsa04062Chemokine signaling pathway0.0187182364P10720, P55774, P02776, P02775,
hsa04611Platelet activation0.094211894P02675, P02679, P02671, P02452,
hsa04060Cytokine-cytokine receptor interaction0.094211894P10720, P55774, P02776, P02775,
hsa00563Glycosylphosphatidylinositol (GPI)-anchor biosynthesis0.208020111P80108,
hsa00410beta-Alanine metabolism0.208020111Q96KN2,
hsa02010ABC transporters0.208020111Q9NP78,
hsa04666Fc gamma R-mediated phagocytosis0.208020111P06396,
hsa00900Terpenoid backbone biosynthesis0.208020111Q9UHG3,
hsa00230Purine metabolism0.208020111P14618,
hsa00340Histidine metabolism0.208020111Q96KN2,
hsa04120Ubiquitin mediated proteolysis0.2756015134P01742, P04438, P01769, P01743,
hsa04810Regulation of actin cytoskeleton0.282036493P02751, O43707, P06396,
hsa05150Staphylococcus aureus infection0.3119404185P08603, P0C0L4, P02679, P06681, P13645,
hsa05146Amoebiasis0.3460206103P02751, O43707, P02452,
hsa05222Small cell lung cancer0.373181721P02751,
hsa04614Renin-angiotensin system0.373181721P01019,
hsa04978Mineral absorption0.373181721P02787,
hsa05412Arrhythmogenic right ventricular cardiomyopathy (ARVC)0.373181721O43707,
hsa05203Viral carcinogenesis0.4095525113P14618, O43707, P06396,
hsa03050Proteasome0.446093172P49721, P25789,

Note. Italic font indicated the candidate protein.