Serum Folate Correlates with Severity of Guillain-Barré Syndrome and Predicts Disease Progression

Table 4

Predictors of a faster GBS progression, defined as reaching nadir weakness in 1 week from onset.

	Univariate analysis		Multivariable analysis
variables	OR (95% CI)	p	OR (95% CI)	p
Age	0.97 (0.95, 1.00)	0.07	0.96 (0.93, 0.99)	0.02
Gender (Female vs. male)	1.16 (0.55, 2.47)	0.70	-	-
Superficial sense deficit (no vs. yes)	2.68 (1.24, 5.80)	0.01	-	-
Deep sensation deficit (no vs. yes)	5.13 (1.33, 19.82)	0.02	5.17 (1.16, 23.09)	0.03
Dyspnea on admission (no vs. yes)	0.31 (0.10, 0.91)	0.03	-	-
MRC score on admission	0.96 (0.93, 0.99)	0.005	0.94 (0.90, 0.98)	0.001
Folate deficiency (no vs. yes)	4.19 (1.49, 11.83)	0.007	6.04 (1.69, 21.61)	0.006

OR, odds ratio; CI, confidence interval; MRC, Medical Research Council