Research Article

Inflammatory Cellular Response to Mechanical Ventilation in Elastase-Induced Experimental Emphysema: Role of Preexisting Alveolar Macrophages Infiltration

Table 2

Bronchoalveolar lavage cellularity in SV and MV mice, 14 and 21 days after saline or elastase tracheal instillation.

D14D21
SalineElastaseSalineElastase
SVMVSVMVSVMVSVMV

Cell count, x104cell/μL8.4±8.711.5±6.58.2±10.69.3±8.89.1±4.411.1±11.311.2±4.911.3±6.8

Definition of abbreviations: SV: spontaneous ventilation; MV: mechanical ventilation.
Values are expressed as median ± interquartile range; n = 5-9 animals/group.
No significant difference was found between groups. Differential cell count showed a predominance of macrophages (>90% of total cells) in all groups.