Molecular Analysis and Modeling of Hepatitis E Virus Helicase and Identification of Novel Inhibitors by Virtual Screening

Table 2

Drug likeness parameters of the selected compounds showing HEV-helicase inhibitory activities.

No.	Compounds (PubChem ID)	MW	HBD	HBA	LogP	RB	Ro5 violation
1	BTB07890	446.288	2	7	3.9	7	0
2	JFD02650	408.428	0	6	3.68	5	0
3	CD07424	360.375	2	8	2.14	6	0
4	SPB07861	417.487	1	6	3.72	8	0
5	HTS03126	481.982	1	6	3.74	6	0
6	RDR03130	396.458	1	7	1.69	8	0
7	HTS11136	387.24	2	6	3.31	7	0
8	JFD02375	458.417	4	10	0.46	4	0
9	KM07751	422.87	0	7	3.84	5	0
10	RJC03167	470.636	0	7	6.1	6	1