Research Article
Correlation between the Expression of PD-L1 and Clinicopathological Features in Patients with Thymic Epithelial Tumors
Table 1
Relationship between the expression of PD-L1 protein and clinicopathological features in TETs.
| Clinicopathological factors | Case number | PD-L1 expression | Positive rate (%) | | value | + | − |
| Gender | | | | | | | Male | 30 | 20 | 10 | 33.33 | 3.243 | 0.092 | Female | 40 | 18 | 22 | 45.00 | Age | | | | | | | ≤50 years | 16 | 7 | 9 | 43.75 | 0.928 | 0.399 | >50 years | 54 | 31 | 23 | 57.41 | Tumor size | | | | | | | ≤4 cm | 41 | 22 | 19 | 53.66 | 0.016 | 1.000 | >4 cm | 29 | 16 | 13 | 55.17 | Histological classification | | | | | | | Type A | 11 | 4 | 7 | 36.36 | 20.648 | 0.001 | Type AB | 13 | 2 | 11 | 15.39 | Type B1 | 9 | 3 | 6 | 33.33 | Type B2 | 7 | 6 | 1 | 85.71 | Type B3 | 10 | 9 | 1 | 90.00 | Type C thymic carcinoma | 20 | 14 | 6 | 70.00 | Masaoka-Koga staging | | | | | | | Stage I | 32 | 10 | 22 | 31.25 | 12.402 | 0.004 | Stage II | 4 | 3 | 1 | 75.00 | Stage III | 20 | 15 | 5 | 75.00 | Stage IV | 14 | 10 | 4 | 71.42 | With/without myasthenia gravis | | | | | | | Yes | 11 | 7 | 4 | 63.64 | 0.460 | 0.533 | No | 59 | 31 | 28 | 52.54 | Metastasis | | | | | | | Yes | 14 | 10 | 4 | 71.43 | 2.072 | 0.231 | No | 56 | 28 | 28 | 50.00 | Radiotherapy | | | | | | | Yes | 37 | 26 | 11 | 70.27 | 8.081 | 0.008 | No | 33 | 12 | 21 | 36.36 | Chemotherapy | | | | | | | Yes | 21 | 16 | 5 | 76.19 | 5.800 | 0.02 | No | 49 | 22 | 27 | 44.90 |
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