Gene Expression Patterns Analysis in the Supraspinatus Muscle after a Rotator Cuff Tear in a Mouse Model

Table 5

Gene expression patterns in the muscle atrophy category after rotator cuff tear ((a) week 1 after tear; (b) week 4 after tear).

(a)

Gene symbol	Genbank accession	Fold change	Gene name
Upregulated
Myog	NM_031189	38.535	myogenin
Gatm	NM_025961	8.862	glycine amidinotransferase (L-arginine:glycine amidinotransferase):energy metabolism of muscle
Cflar	NM_009805	2.442	CASP8 and FADD-like apoptosis regulator
Rps6kb1	NM_028259	1.287	ribosomal protein S6 kinase, polypeptide 1
Downregulated
Il15	NM_008357	0.727	interleukin 15
Tbce	NM_178337	0.648	tubulin-specific chaperone E
Gsn	NM_146120	0.439	Gelsolin:actin-binding protein
Trim63	NM_001039048	0.435	tripartite motif-containing 63
Actn3	NM_013456	0.279	actinin alpha 3:alpha-actinin skeletal muscle isoform 3
Ppargc1a	NM_008904	0.216	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Mstn	NM_010834	0.108	myostatin

(b)

Gene symbol	Genbank accession	Fold change	Gene name
Upregulated
Myog	NM_031189	11.945	myogenin
Gatm	NM_025961	1.712	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
Gsn	NM_146120	1.249	gelsolin
Rps6kb1	NM_028259	1.245	ribosomal protein S6 kinase, polypeptide 1
Downregulated
Il15	NM_008357	0.98	interleukin 15
Cflar	NM_207653	0.935	CASP8 and FADD-like apoptosis regulator
Ppargc1a	NM_008904	0.763	peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
Tbce	NM_178337	0.712	tubulin-specific chaperone E
Actn3	NM_013456	0.494	actinin alpha 3
Trim63	NM_001039048	0.387	tripartite motif-containing 63
Mstn	NM_010834	0.378	myostatin