Gene Expression Patterns Analysis in the Supraspinatus Muscle after a Rotator Cuff Tear in a Mouse Model

Table 6

Gene expression patterns in the fatty acid transport category after rotator cuff tear ((a) week 1 after tear; (b) week 4 after tear).

(a)

Gene symbol	Genbank accession	Fold change	Gene name
Upregulated
Mfsd2a	NM_029662	12.606	major facilitator superfamily domain containing 2A
Apoe	NM_009696	12.229	apolipoprotein E
Drd4	NM_007878	10.607	dopamine receptor D4
Slc27a6	NM_001081072	7.557	solute carrier family 27 (fatty acid transporter), member 6
Pla2g4a	NM_008869	6.457	phospholipase A2, group IVA (cytosolic, calcium-dependent)
Anxa1	NM_010730	5.517	annexin A1
Plin2	NM_007408	5.018	perilipin 2
Pla2g2e	NM_012044	3.407	phospholipase A2, group IIE
Pla2g1b	NM_011107	3.384	phospholipase A2, group IB, pancreas
Hnf1a	M57966	2.029	HNF1 homeobox A
Downregulated
Fabp3	NM_010174	0.131	fatty acid binding protein 3, muscle and heart
Pla2g5	NM_001122954	0.15	phospholipase A2, group V
Cpt1b	NM_009948	0.186	carnitine palmitoyltransferase 1b, muscle
Pla2g12a	NM_183423	0.262	phospholipase A2, group XIIA
Got2	NM_010325	0.289	glutamic-oxaloacetic transaminase 2, mitochondrial
Slc27a2	NM_011978	0.299	solute carrier family 27 (fatty acid transporter), member 2
Slc27a1	NM_011977	0.32	solute carrier family 27 (fatty acid transporter), member 1
Acsl1	NM_007981	0.354	acyl-CoA synthetase long-chain family member 1
Pnpla8	NM_026164	0.372	patatin-like phospholipase domain containing 8
Pla2g2c	NM_008868	0.408	phospholipase A2, group IIC

(b)

Gene symbol	Genbank accession	Fold change	Gene name
Upregulated
Nmur2	NM_153079	3.742	neuromedin U receptor 2
Apoe	NM_009696	2.729	apolipoprotein E
Pla2g2d	NM_011109	2.704	phospholipase A2, group IID
Pparg	NM_011146	1.56	peroxisome proliferator activated receptor gamma
Proca1	XM_006532963	1.548	protein interacting with cyclin A1
Pla2g2e	NM_012044	1.539	phospholipase A2, group IIE
Pla2g4a	NM_008869	1.485	phospholipase A2, group IVA; (cytosolic, calcium-dependent)
Anxa1	NM_010730	1.377	annexin A1
Pla2g2a	NM_001082531	1.286	phospholipase A2,; group IIA (platelets, synovial fluid)
Mfsd2a	NM_029662	1.268	major facilitator superfamily; domain containing 2A
Downregulated
Pla2g1b	NM_011107	0.428	phospholipase A2, group IB,; pancreas
Slc27a5	NM_009512	0.456	solute carrier family 27 (fatty acid; transporter),; member 5
Pla2g3	NM_172791	0.511	phospholipase A2, group III
Hnf1a	M57966	0.529	HNF1 homeobox A
Fabp3	NM_010174	0.587	fatty acid-binding protein 3, muscle and heart
Pla2g2f	NM_012045	0.592	phospholipase A2, group IIF
Abcc4	NM_001033336	0.592	ATP-binding cassette, sub-family C (CFTR/MRP), member 4
Pnpla8	NM_026164	0.614	patatin-like phospholipase domain containing 8
Ppard	NM_011145	0.628	peroxisome proliferator activator receptor delta
Pla2g5	NM_001122954	0.661	phospholipase A2, group V