Research Article

A Retrospective Study of Cytology, High-Risk HPV, and Colposcopy Results of Vaginal Intraepithelial Neoplasia Patients

Table 4

Detailed cytology results of VaIN diagnosed in patients after hysterectomy and with no hysterectomy.

VaINCytology number (%)Sensitivity (%)
NILMASC-USLSILASC-HHSILCA

VaIN with uterus132 (40.5%)71 (21.8%)108 (33.1%)6 (1.8%)8 (2.5%)1 (0.3%)59.5%
 VaIN2/314 (41.2%)7 (20.6%)10 (29.4%)1 (2.9%)1 (2.9%)1 (2.9%)58.8%
 VaIN1118 (40.4%)64 (21.9%)98 (33.6%)5 (1.7%)7 (2.4%)0 (0.0%)59.6%

 Only VaIN101 (47.6%)50 (23.6%)56 (26.4%)3 (1.4%)2 (0.9%)0 (0.0%)52.4%
 VaIN2/311 (57.9%)4 (21.1%)3 (15.8%)1 (5.3%)0 (0.0%)0 (0.0%)42.1%
 VaIN190 (46.6%)46 (23.8%)53 (27.5%)2 (1.0%)2 (1.0%)0 (0.0%)53.4%

 Concomitant VaIN31 (27.2%)21 (18.4%)52 (45.6%)3 (2.6%)6 (5.3%)1 (0.9%)72.8%
 VaIN2/33 (20.0%)3 (20.0%)7 (46.7%)0 (0.0%)1 (6.7%)1 (6.7%)80.0%
 VaIN128 (28.3%)18 (18.2%)45 (45.5%)3 (3.0%)5 (5.1%)0 (0.0%)71.7%

VaIN after hysterectomy24 (30.4%)16 (20.3%)24 (30.4%)4 (5.1%)11 (13.9%)0 (0.0%)69.6%
 VaIN2/35 (19.2%)3 (11.5%)3 (11.5%)4 (15.4%)11 (42.3%)0 (0.0%)80.8%
 VaIN119 (35.8%)13 (24.5%)21 (39.6%)0 (0.0%)0 (0.0%)0 (0.0%)64.2%

VaIN: vaginal intraepithelial neoplasia; NILM: negative for intraepithelial lesion or malignancy; ASCUS: atypical squamous cells of undetermined significance; LSIL: low-grade squamous intraepithelial lesion; ASC-H: atypical squamous cells cannot exclude HSIL; HSIL: high-grade squamous intraepithelial lesion; CA: cancer.