Global, Survival, and Apoptotic Transcriptome during Mouse and Human Early Embryonic Development

Figure 2

The predicted top regulator effects networks in the MII versus EGA, MII versus BL, and EGA versus BL stages in human (left) and mouse (right). Upstream regulators are displayed in the top tier while diseases and functions are displayed in the bottom. The dataset genes that connect the upper regulator to the lower diseases and functions are in the middle tier and causal relationships are displayed with blue (inhibition) and orange (activation) line. Significant upregulated and downregulated genes from the dataset genes are in red and green, respectively. The color intensities of the connected genes were proportional to their fold changes.