Research Article

Prognostic Value of Immunoscore and PD-L1 Expression in Metastatic Colorectal Cancer Patients with Different RAS Status after Palliative Operation

Table 1

Basic characteristics of the recruited mCRC patients.

Characteristics TotalRAS mutationImmunoscorePD-L1 expression
Mutation typeWild type valueLowHigh valueNegativePositive value

Patients number  (percentage) 6026 
(43.33%)
34 
(56.67%)
38 
(63.33%)
22 
(36.67%)
34 
(56.67%)
26 
(43.33%)
Age0.3410.3250.207
 Mean ± SD59.64 ± 10.6859.15 ± 10.5159.84 ± 10.1659.22 ± 11.5359.41 ± 8.8559.88 ± 12.69
Sex0.8320.2940.429
 Male43192429142320
 Female1771098116
Location0.0540.8510.002
 Right161150.0171150.6001060.582
 Left19712127163
 Rectum258170.13415100.6518170.001
Site of metastasis
 Liver5322310.43334190.71830230.978
 Lung11740.133740.982830.234
 Others4220.781220.567220.781

Age was compared between two groups by using independent -test; values are calculated by using Fisher’s exact test because less than 80% of the cells have an expected frequency of 5 or greater, or any cell has an expected frequency smaller than 1.0.