Prognostic Value of Immunoscore and PD-L1 Expression in Metastatic Colorectal Cancer Patients with Different RAS Status after Palliative Operation
Table 1
Basic characteristics of the recruited mCRC patients.
Characteristics
Total
RAS mutation
Immunoscore
PD-L1 expression
Mutation type
Wild type
value
Low
High
value
Negative
Positive
value
Patients number (percentage)
60
26 (43.33%)
34 (56.67%)
38 (63.33%)
22 (36.67%)
34 (56.67%)
26 (43.33%)
Age
0.341
0.325
0.207
Mean ± SD
59.64 ± 10.68
59.15 ± 10.51
59.84 ± 10.16
59.22 ± 11.53
59.41 ± 8.85
59.88 ± 12.69
Sex
0.832
0.294
0.429
Male
43
19
24
29
14
23
20
Female
17
7
10
9
8
11
6
Location
0.054
0.851
0.002
Right
16
11
5
0.017
11
5
0.600
10
6
0.582
Left
19
7
12
12
7
16
3
Rectum
25
8
17
0.134
15
10
0.651
8
17
0.001
Site of metastasis
Liver
53
22
31
0.433
34
19
0.718
30
23
0.978
Lung
11
7
4
0.133
7
4
0.982
8
3
0.234
Others
4
2
2
0.781
2
2
0.567
2
2
0.781
Age was compared between two groups by using independent -test; values are calculated by using Fisher’s exact test because less than 80% of the cells have an expected frequency of 5 or greater, or any cell has an expected frequency smaller than 1.0.