PTX3: A Potential Biomarker in Thyroid Associated Ophthalmopathy

Table 2

Gene expression of predicted functional partners of PTX3 in orbital adipose tissue from patients with TAO and controls. Differential expression was identified in orbital adipose tissue collected from 10 patients with TAO and 5 controls and subjected to RNA-seq analysis.

Gene	Description	(TAO versus control)	FDR
TNFAIP6	Tumor necrosis factor, alpha-induced protein 6.; Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis.	1.48	0.027
FCN1	Ficolin (collagen/fibrinogen domain containing) 1.	2.13	0.0001

Note. Functionally related proteins were identified by experiments and text mining (http://string-db.org).