Peptide Extract from Olivancillaria hiatula Exhibits Broad-Spectrum Antibacterial Activity

Table 3

Co-modulation studies: MICs of ciprofloxacin plus 20 μg/mL of peptide extract.

Organism	MIC (μg/mL)		MF	Change in MIC (%)
	Cip	Cip + P
E. coli (-)	1.95	0.00095	2053	99.95^R
K. pneumonia (-)	0.00095	0.00012	8	87.50^R
S. paratyphi (-)	125.00	0.00763	16383	99.99^R
P. mirabilis (-)	0.00048	0.00003	16	50.00^R
N. gonorrhea (-)	125.00	62.5	2	50.00^R
V. cholera (-)	3.91	0.00095	4116	99.98^R
P. aeruginosa (-)	0.24	0.00191	126	99.99^R
S. aureus (+)	15.63	1.95	8	87.50^R
E. faecalis (+)	0.24	0.0038	64	98.44^R

MIC experiments were replicated thrice; change in MIC computed using equation (2).
MF: modulation factor, Cip: ciprofloxacin, P: peptide extract, and R: reduction in MIC