Peptide Extract from Olivancillaria hiatula Exhibits Broad-Spectrum Antibacterial Activity

Table 5

Co-modulation studies: MICs of Erythromycin plus 20 μg/mL of peptide extract.

Organism	MIC (μg/mL)		MF	Change in MIC (%)
	Eryt	Eryt + CP
E. coli	125	125	1	N
K. pneumonia	7.8	>7.8	<1	> 100^I
S. paratyphi	250	>500	<0.50	> 100^I
P. mirabilis	125	250	0.50	100^I
N. gonorrhea	500	>500	<1	> 100^I
V. cholera	125	>500	<0.25	>100^I
P. aeruginosa	125	>500	<0.25	>100^I
S. aureus	>500	>500	<1.00	> 100^I
E. faecalis	0.24	>7.8	<0.03	>100^I

MIC experiments were replicated thrice; change in MIC computed using equation (2).
MF: modulation factor, Eryt: erythromycin, P: peptide extract, N: no change, and I: increase in MIC