Peptide Extract from Olivancillaria hiatula Exhibits Broad-Spectrum Antibacterial Activity

Table 6

Co-modulation studies: MIC values of mtronidazole plus 20 μg/mL of peptide extract.

Organism	MIC (μg/mL)
	Met	Met + CP	MF	Change in MIC (%)
E. coli	>500	>500	<1	> 100^I
K. pneumonia	>500	>500	<1	> 100^I
S. paratyphi	>500	>500	<1	> 100^I
P. mirabilis	>500	>500	<1	> 100^I
N. gonorrhea	>500	>500	<1	> 100^I
V. cholera	>500	>500	<1	> 100^I
P. aeruginosa	>500	>500	<1	> 100^I
S. aureus	>500	>500	<1	> 100^I
E. faecalis	>500	250	>1	<50^R

MIC experiments were replicated thrice; change in MIC computed using equation (2).
MF: modulation factor, Met: Metronidazole, P: peptide extract, R: reduction in mic, and I: increase in MIC