Research Article
Manifestations and Outcomes of Patients with Parkinson’s Disease and Serious Infection in the Emergency Department
Table 1
Demographics and clinical characteristics of septic patients with or without Parkinson’s disease.
| | Variable | Non-PD | PD | P value | | (n = 2,400) | (n = 1,200) |
| | Age, mean ± SD | 77.3 ± 8.8 | 77.3 ± 8.8 | 0.997 | | Sex, male, n (%) | 1313 (54.7%) | 623 (51.9%) | 0.119 | | Vital signs at ED (mean ± SD) | | | | | Body temperature (°C) | 37.3 ± 1.1 | 37.5 ± 1.2 | <0.00 | | Heart rate (beats per minute) | 99.3 ± 23.4 | 98.8 ± 21.9 | 0.484 | | Systolic blood pressure (mmHg) | 140.4 ± 36.8 | 138.9 ± 34.8 | 0.239 | | Diastolic blood pressure (mmHg) | 80.2 ± 29.5 | 79.9 ± 33.3 | 0.834 | | Respiratory rate (breaths per minute) | 20.4 ± 3.9 | 20.4 ± 3.6 | 0.972 | | Major comorbidities, n (%) | | | | | Liver cirrhosis | 186 (7.8%) | 33 (2.8%) | <0.00 | | Hypertension | 1156 (48.2%) | 605 (50.4) | 0.203 | | Diabetes mellitus | 863 (36.0%) | 443 (36.9%) | 0.581 | | Chronic renal insufficiency | 247 (10.3%) | 115 (9.6%) | 0.518 | | Congestive heart failure | 271 (11.3%) | 71 (5.9%) | <0.00 | | Malignancy | 547 (22.8%) | 114 (9.5%) | <0.00 | | Hematologic disorder | 58(2.4%) | 9(0.8%) | <0.00 | | Autoimmune disease | 33(1.4%) | 7(0.6%) | 0.04 | | Major source of infection, n (%) | | | | | Respiratory tract | 1046 (43.6%) | 594 (49.5%) | 0.00 | | Urinary tract | 559 (23.3%) | 583 (48.6%) | <0.00 | | Soft tissue infection | 143 (6.0%) | 87 (7.2%) | 0.148 | | Meningitis | 21 (0.9%) | 5 (0.4%) | 0.147 | | Intra-abdominal infection | 87 (3.6%) | 17 (1.4%) | <0.00 | | Biliary tract infection | 170 (7.1%) | 29 (2.4%) | <0.00 | | Others | 656 (27.3%) | 140 (11.7%) | <0.00 | | Bacteremia, n (%) | 331 (13.8%) | 161 (13.4%) | 0.797 | | Days of admission (mean ± SD) | 15.4 ± 13.5 | 17.8 ± 13.0 | <0.00 | | Days of admission (survivors only) | 15.5 ± 13.0 | 18.1 ± 12.9 | <0.00 | | ICU admission, n (%) | 306 (12.8%) | 124 (10.3%) | 0.03 | | Septic shock within 72 hours, n (%) | 174 (7.2%) | 60 (5.0%) | 0.01 | | Respiratory failure within 72 hours, n (%) | 365 (15.2%) | 122 (10.2%) | <0.00 | | 28-day in-hospital mortality, n (%) | 339 (14.1%) | 86 (7.2%) | <0.00 |
|
|
PD: Parkinson’s disease; ED: emergency department; SD: standard deviation; ICU: intensive care unit < 0.05 |
