Multiple Low Frequency Ultrasound Enhances Bactericidal Activity of Vancomycin against Methicillin-Resistant Staphylococcus aureus Biofilms

Figure 2

The effect of intensity and irradiation time on the bactericidal effect of S-LFU. Biofilms on disks were incubated at 37°C for 2 days. The biofilms of the three bacterial strains were treated with S-LFU with different intensity (92.36, 138.54, and 184.72 mW/cm²) and irradiation time (5 or 15 min). The viable bacterial counts in biofilms were determined right after ultrasound and at 24 hours following ultrasound. <0.05, as compared with the control group.