Mammographic Breast Density and Breast Cancer Molecular Subtypes: The Kenyan-African Aspect

Table 1

Select characteristics of breast cancer patients with pretreatment diagnostic mammograms, Aga Khan University Hospital, Kenya, 2014-2015.

Clinical characteristic	Overall ()		ER-positive		ER-negative
		(%)		(%)		(%)
Age
<50 years	48	39	37	41	11	33
≥50 years	75	61	53	59	22	67
Mean (years), SD	54 (11)		53 (11)		57 (12)
Median (range)	54 (27-83)		54 (27-81)		54 (39-83)
Menopausal status
Pre	42	34	33	37	9	27
Post	81	66	57	63	24	73
BMI category
Lean	18	15	13	14	5	15
Overweight	54	44	40	44	14	42
Obese	43	35	32	36	11	33
Missing	8	7	5	6	3	9
Mean (kg/m^2), SD	29 (4.8)		29 (4.7)		28 (5.3)
Median (range)	28 (18-46.8)		28 (19-45.6)		28 (18-46.8)
Diagnosis
Invasive ductal	105	85	77	86	28	85
Other	18	15	13	14	5	15
Tumor size
<3 cm	53	43	44	49	9	27
≥3 cm	58	47	39	43	19	58
Missing	12	10	7	8	5	15
Mean (cm), SD	3.3 (1.8)		3.3 (1.8)		3.4 (1.9)
Median (range)	3 (0.5-10)		2.7 (1-10)		3 (0.5-8)
Tumor grade
Grade 1	14	11	13	14	1	3
Grade 2	57	46	51	57	6	18
Grade 3	49	40	25	28	24	73
Missing	3	2	1	1	2	6
Nodal status
Negative	49	40	36	40	13	39
Positive	60	49	46	51	14	42
Missing	14	11	8	9	6	18
PR status
Negative	40	33	9	10	31	94
Positive	83	67	81	90	2	6
HER2 status
Negative	94	76	71	79	23	70
Positive	22	18	14	16	8	24
Equivocal/DCIS	7	6	5	6	2	6
TNBC status
Negative	95	77	85	94	10	30
Positive	21	17	0	0	21	64
Missing	7	6	5	6	2	6

BMI: body mass index; ER: estrogen receptor; HER2: human epidermal growth factor receptor 2; PR: progesterone receptor; TNBC: triple negative breast cancer.