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BioMed Research International
Volume 2018, Article ID 6038106, 7 pages
https://doi.org/10.1155/2018/6038106
Clinical Study

The Assessment of the Integrated Antioxidant System of the Body in the Course of Radon Therapy: A Pilot Study

1Department of Physiotherapy, Medical University of Wroclaw, Wroclaw, Poland
2Department of Professional Training in Clinical Chemistry, Medical University of Wroclaw, Wroclaw, Poland
3Department of Diagnostics Laboratory for Teaching and Research, Medical University of Wroclaw, Wroclaw, Poland

Correspondence should be addressed to Michał Kasperczak; moc.liamg@dmkazcrepsakm

Received 7 January 2017; Revised 8 March 2017; Accepted 14 March 2017; Published 2 January 2018

Academic Editor: Swaran J. S. Flora

Copyright © 2018 Jadwiga Kuciel-Lewandowska et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction. The sources of Reactive Oxidative Species (ROS) in the organism are the respiratory processes occurring in cells catalyzed by different enzymes. Operation of ROS is balanced by antioxidants, the compounds; although present in low concentrations, they significantly inhibit the degree of oxidation of particular molecules. The Aim of the Study. The aim of this study was to assess the changes in the integrated antioxidant system under the influence of radon therapy in osteoarthritis patients. Material and Methods. Observation included 35 patients suffering from degenerative joints and disc disease (mean age 56.5 years) undergoing radon water therapy and control group that consisted of 15 osteoarthritis patients (mean age 54.2) without contact with radon water. Before therapy and after 18 days of treatment, serum total antioxidant status (TAS) was assessed with the use of standard colorimetric assay. Results. In the study group, we observed trends to increase TAS concentration, whereas, in the control group, TAS concentration was decreasing. Conclusions. (1) Radon waters treatment influenced the level of TAS of osteoarthritis patients treated with the radon water. (2) The change in TAS concentrations in the study group may be the result of low doses of ionizing radiation, but further studies on larger patient’s groups are demanded. This study is registered with number NCT03274128.