Research Article

The Therapeutic Effects after Transplantation of Whole-Layer Olfactory Mucosa in Rats with Optic Nerve Injury

Figure 2

The effects of whole-layer olfactory mucosa transplantation on RGC survival after ONI. (a) For the sagittal plane of retinas, one field from at least eight areas (~350 μm) across the sections was imaged to quantify the numbers of RGCs. Scale bar, 1000 μm. (b) Representative images of retinal sections stained with anti-Tuj1 (in green) antibodies and DAPI (in blue) showing survival of RGCs in sham group rats, OM group rats, and NC group rats at 14 days after crush injury. Scale bar, 50 μm. (c) Quantification of RGC survival at 3, 7, 14, and 28 days after crush injury. The numbers of RGCs are presented as the mean ± SD (). , compared to NC group, ANOVA with Bonferroni posttest.