Current Strategies of Endocrine Therapy in Elderly Patients with Breast Cancer

Table 2

Endocrine therapy of the elderly with breast cancer.

Hormone agent	Mechanism	Dose
Letrozole	Reversible AIs	2.5 mg daily PO
Anastrozole	Reversible AIs	1 mg daily PO
Exemestane	Irreversible AI	25 mg daily PO
Fulvestrant	SERD	500 mg IM q 28 days
Everolimus	mTOR inhibitor	10 mg daily PO
Palbociclib	CDK 4/6 inhibitor	125 mg daily PO

AI, aromatase inhibitor; SERD, selective estrogen receptor downregulator; mTOR, mammalian target of rapamycin; CDK, cyclin dependent kinase.