Research Article
Pontin Acts as a Potential Biomarker for Poor Clinical Outcome and Promotes Tumor Invasion in Hilar Cholangiocarcinoma
Table 1
Relationships between the expression of Pontin and clinicopathological features in human hilar cholangiocarcinoma.
| Clinicopathological features | | Pontin | | Low | High |
| Gender | | | | 0.451 | Male | 54 | 31 | 23 | | Female | 32 | 21 | 11 | | Age (years) | | | | 0.329 | <60 | 41 | 27 | 14 | | ≥60 | 45 | 25 | 20 | | Differentiation | | | | 0.062 | Well/moderately | 51 | 35 | 16 | | Poorly | 35 | 17 | 18 | | Bismuth–Corlette classification | | | | 0.624 | Type I | 22 | 13 | 9 | | Type II | 11 | 9 | 2 | | Type IIIa | 12 | 7 | 5 | | Type IIIb | 15 | 9 | 6 | | Type IV | 26 | 14 | 12 | | Tumor size (cm) | | | | 0.299 | <3 | 31 | 16 | 15 | | 3–5 | 19 | 14 | 5 | | ≥5 | 36 | 22 | 14 | | Tumor stage | | | | 0.127 | T1 | 20 | 9 | 11 | | T2 | 27 | 20 | 7 | | T3 | 39 | 23 | 16 | | Lymph node metastasis | | | | 0.011 | No | 59 | 41 | 18 | | Yes | 27 | 11 | 16 | | TNM stage | | | | 0.005 | I | 23 | 19 | 4 | | II | 20 | 15 | 5 | | IIIa | 16 | 7 | 9 | | IIIb | 27 | 11 | 16 | |
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