Overexpression of TRIM24 Stimulates Proliferation and Glucose Metabolism of Head and Neck Squamous Cell Carcinoma

Figure 3

TRIM24 regulates cell proliferation, colony formation, and invasion. (a) CCK-8 assay showed that TRIM24 overexpression promoted while its depletion inhibited cell growth rate. (b) Colony formation assay was performed in cells transfected with TRIM24 siRNA and plasmid. An increase of colony number was found in cells transfected with plasmid. A decrease in colony formation was seen in the groups with siRNA treatment in comparison with the controls. (c) TRIM24 overexpression greatly facilitated cell invasion, while TRIM24 depletion remarkably blocked invasion.

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