Research Article

Risk Factors for Neonatal Sepsis: A Retrospective Case-Control Study among Neonates Who Were Delivered by Caesarean Section at the Trauma and Specialist Hospital, Winneba, Ghana

Table 1

Association between neonatal characteristics and neonatal sepsis.

VariableCasesControlsTotalChi-square, 2 (p-value)
n=67()n=316()N=383()

Gestational age (weeks)
<3716 (23.9)42 (13.3)58 (15.1)
37-4249 (73.1)258 (81.6)307 (80.2)5.10 (0.078)
>422 (3.0)16 (5.1)18 (4.7)
Birth weight (Kg)
<1.59 (13.4)17 (5.4)26 (6.8)
1.5-2.59 (13.4)64 (20.2)73 (19.1)6.64 (0.036)
>2.549 (73.2)235 (74.4)284 (74.1)
Sex
Male34 (50.8)153 (48.4)187 (48.8)
Female33 (49.2)163 (51.6)196 (51.2)0.12 (0.729)
Neonatal age (Days)
<755 (82.1)128 (40.5)183 (47.8)38.31 (<0.001)
≥712 (17.9)188 (59.5)200 (52.2)
APGAR score in the first minute
<727 (40.3)96 (30.4)123 (32.1)2.49 (0.114)
≥740 (59.7)220 (69.6)260 (67.9)
APGAR score in the fifth minute
<717 (25.4)58 (18.3)75 (19.6)1.73 (0.789)
≥750 (74.6)258 (81.7)308 (80.4)
Meconium
None8 (11.9)108 (34.2)116 (30.3)
Passed59 (88.1)208 (65.8)267 (69.7)12.95 (<0.001)
No55 (82.1)254 (80.4)309 (80.7)
Yes12 (17.9)62 (19.6)74 (19.3)0.10 (0.747)
Reason for CS
Emergency60 (89.5)182 (57.6)242 (63.2)
Elective7 (10.5)134 (42.4)141 (36.8)24.27 (<0.001)
Duration of stay
< 1 week48 (71.6)290 (91.8)338 (88.3)
1-2 weeks8 (11.9)22 (7.0)30 (7.8)
<2 weeks11 (16.5)4 (1.2)15 (3.9)36.69 (<0.001)
Outcome of admission
Discharged61 (91.0)300 (94.9)361 (94.3)
Died4 (6.0)13 (4.1)17 (4.4)
Referred2 (3.0)3 (1.0)5 (1.3)2.27 (0.321)