Efficient Biocatalytic Synthesis of Chiral Intermediate of Pregabalin Using Immobilized<i> Talaromyces thermophilus</i> Lipase

<div>Effect of temperature on activity (a) and thermostability (b) of immobilized and free TTL mutant. The reaction mixture (pH 8.0) was composed of 100 mM Tris-HCl, 100 mM CNDE and 5 mM zinc acetate. Symbols: filled triangle, free TTL mutant; filled diamond, immobilized TTL mutant; filled square, immobilized TTL mutant at 50°C; filled circle, free TTL mutant at 50°C; square, immobilized TTL mutant at 35°C; circle, free TTL mutant at 35°C.</div>

BioMed Research International

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Figure 4: Efficient Biocatalytic Synthesis of Chiral Intermediate of Pregabalin Using Immobilized<i> Talaromyces thermophilus</i> Lipase 

BioMed Research International

Efficient Biocatalytic Synthesis of Chiral Intermediate of Pregabalin Using Immobilized Talaromyces thermophilus Lipase

Figure 4