Efficient Biocatalytic Synthesis of Chiral Intermediate of Pregabalin Using Immobilized Talaromyces thermophilus Lipase

Table 1

Comparison of CNDE resolution between immobilized TTL mutant and other lipases.

Enzyme source	Substrate concentration (M)	Conversion	Space-time yield	Reference
		(%)	(g/L/h)
Thermomyces lanuginosus lipase	3	47.5	12.9	[28]
Thermomyces lanuginosus lipase	3	45.2	12.8	[32]
Pseudomonas esterase	0.5	47.7	7.7	[33]
Talaromyces thermophilus lipase	3	49.7	112.8	This work