De Novo Endotoxin-Induced Production of Antibodies against the Bile Salt Export Pump Associated with Bacterial Infection following Major Hepatectomy

<div><i>Examination of hepatobiliary transporter compounds</i>. (a) Immunohistochemical staining of bile salt export pump (BSEP) in liver tissue showed no difference, even when compared with normal control liver (20x). From left to right: normal liver tissue without hepatectomy and LPS exposure, liver tissue with hepatectomy plus LPS 200 ng at postoperative day 4, liver tissue with hepatectomy plus LPS 500 ng at postoperative day 2, and liver tissue with hepatectomy plus 500 ng LPS at postoperative day 4. (b) The mRNA expression levels of MRP2, MRP3, MRP4, BSEP, and Ntcp were examined, and no significant differences were observed between groups.</div>

BioMed Research International

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Figure 2

Figure 2: De Novo Endotoxin-Induced Production of Antibodies against the Bile Salt Export Pump Associated with Bacterial Infection following Major Hepatectomy 

Figure 2 | De Novo Endotoxin-Induced Production of Antibodies against the Bile Salt Export Pump Associated with Bacterial Infection following Major Hepatectomy 