The Detection and Phylogenetic Analysis of Bovine Hepacivirus in China

Figure 1

Phylogenetic analysis of the BovHepV isolates identified in this study and other hepaciviruses from human and various animal species. The neighbor-joining tree was constructed based on 310 nt in the coding sequences of NS3 of hepaciviruses. Bootstrap analysis was performed with 1,000 replicates (the numbers close to the branches are percentages), the Tamura three-parameter model, and transitions + transversions. Sequences from the GenBank database are cited with their accession numbers. Sequences are identified as follows: empty blue circle, bovine hepacivirus; empty orange circle, novel bovine hepacivirus; filled blue circle, BovHepV in this study; filled black inverted triangle, hepacivirus from black-and-white colobus; filled black square, hepacivirus from Rattus norvegicus; empty black inverted triangle, hepacivirus from Hipposideros vittatus; empty black square, hepacivirus from Rattus norvegicus; empty red diamond, hepacivirus from bat; empty black triangle, hepacivirus from human; filled black triangle, hepacivirus from horse; filled black circle, hepacivirus from rodent; filled red diamond, hepatitis GB virus A.