Research Article

Aphrodisiac Activity of Eulophia macrobulbon Extract on Erectile Dysfunction in Male Aged Rats

Table 1

Effects of 21-day administration of vehicle, EM (15, 150, and 450 mg/kg BW), or sildenafil citrate (5 mg/kg BW) on mating behavior in age-related ED rats.

GroupParameter
ML (min)MFIL (min)IFEL (min)EF

Young control0.45 ± 0.111.70 ± 2.381.22 ± 0.2448.50 ± 6.388.01 ± 2.531.20 ± 0.29
Aged control1.55 ± 0.3412.35 ± 4.315.39 ± 2.3420.90 ± 3.8027.93 ± 1.160.33 ± 0.21
Aged + EM150.55 ± 0.1611.20 ± 3.590.77 ± 0.1528.35 ± 3.11##21.83 ± 3.090.85 ± 0.32
Aged + EM1500.21 ± 0.057.20 ± 1.450.83 ± 0.3727.40 ± 3.39##19.83 ± 2.061.30 ± 0.29
Aged + EM4500.55 ± 0.2210.10 ± 3.031.13 ± 0.2725.50 ± 1.70##20.99 ± 2.341.40 ± 0.33
Aged + sildenafil0.45 ± 0.1211.55 ± 2.291.15 ± 0.2529.20 ± 2.68##20.13 ± 2.521.20 ± 0.29

ML: mount latency; MF: mount frequency; IL: intromission latency; IF: intromission frequency; EL: ejaculation latency; EF: ejaculation frequency. Latencies are expressed in minutes (min), and frequencies are expressed as number of events. Data are expressed as the mean ± SEM; N=10; P < 0.05, P < 0.01, and P < 0.001 response significantly different compared with aged control group; ##P < 0.01 response significantly different compared with young control group.