Insecticide Resistance and Fitness: The Case of Four Aedes aegypti Populations from Different Brazilian Regions
Table 2
Temephos and deltamethrin resistance ratios (RR95) and the 95% confidence interval estimated in four Brazilian Ae. aegypti populations. The allelic frequencies of the kdr mutation Val1016Ile (pyrethroid target site) and enzymatic activities (MFO, EST with three different substrates, and GST) are also shown.
Municipality/State
Sample
RR95 Temephosa
RR95 Deltamethrina
NaV Val1016Ilea
MFOa
-ESTa
-ESTa
NPA-ESTa
GSTa
Campo Grande/MS
Feb-2010
7.9 (7.3-8.6)
97.8 (83.9-119.6)
0.860
3
5
14
14
76
Jun-2010
5.8 (5.3-6.3)
58.2 (54.6-62.7)
0.973
18
7
35
Oct-2010
4.6 (4.1-5.3)
88.3 (76.5-106.7)
0.911
3
27
44
1
30
Jan-2011
4.6 (4.2-5.0)
85.5 (76.8-97.3)
0.817
10
8
34
4
16
Duque de Caxias/RJ
Feb-2010
13.3 (12.4-14.5)
61.3 (53.1-73.3)
0.929
38
17
62
81
May-2010
10.7 (10.1-11.4)
79.4 (68.7-95.2)
0.923
10
57
33
Aug-2010
10.9 (10.2-11.7)
64.4 (54.1-80.1)
0.759
21
45
24
22
46
Nov/2010
9.8 (9.2-10.5)
44.5 (40.1-50.0)
0.907
15
24
7
26
34
Parnamirim/RN
Feb-2010
7.1 (6.6-7.8)
11.6 (7.9-17.8)
0.017
12
6
34
80
May-2010
6.4 (6.1-6.9)
10.1 (8.9-11.8)
0.000
14
43
44
Aug-2010
6.3 (5.9-6.8)
12.4 (11.2-14.1)
0.017
14
39
36
7
27
Dec-2010
6.3 (6.0-6.7)
14.2 (13.0-16.0)
0.017
5
31
13
23
70
Santarém/PA
Apr-2010
10.2 (8.7-12.2)
57.7 (50.3-67.9)
0.000
7
0
11
11
48
Jul-2010
10.3 (9.7-10.9)
35.1 (32.6-38.3)
0.000
31
20
16
Oct-2010
8.6 (8-9.2)
55.1 (35.5-82.1)
0.000
2
3
15
9
16
Jan-2011
9.0 (8.4-9.6)
49.3 (56.8-44.0)
0.000
14
3
9
3
3
aData originally reported by [33]. Enzymatic activities (MFO, EST with three different substrates, and GST) were classified as normal (regular font), altered (italic and underlined font), or highly altered (italic and bold) if these values ranged, respectively, below 15%, between 15 and 50%, or above 50%.
