Research Article
Rs4612666 Polymorphism of the NLRP3 Gene Is Associated with the Occurrence of Large Artery Atherosclerotic Ischemic Strokes and Microembolic Signals
Table 2
Clinical characteristics of LAA patients and control subjects.
| | Variables | LAA group
| Control group
| value |
| | Age (years) | 62.89 ± 12.58 | 61.27 ± 10.32 | 0.097 | | Sex (man,%) | 219 (74.7%) | 150 (56.6%) | <0.001 | | Hypertension (, %) | 200 (68.3%) | 122 (46.0%) | <0.001 | | Diabetes (, %) | 86 (29.4%) | 46 (17.4%) | 0.001 | | CAD (, %) | 68 (23.2%) | 65 (24.5%) | 0.715 | | Smoking (, %) | 143 (48.8%) | 54 (20.4%) | <0.001 | | Drinking (, %) | 121 (41.3%) | 56 (21.1%) | <0.001 | | Family history of cerebro-cardiovascular events (, %) | 61 (20.8%) | 19 (7.2%) | <0.001 | | BMI (kg/m2) | 23.98 ± 3.96 | 23.87 ± 3.73 | 0.727 | | TG (mmol/L) | 1.56 ± 0.89 | 1.79 ± 1.09 | 0.008 | | TC (mmol/L) | 4.46 ± 1.14 | 4.80 ± 0.98 | <0.001 | | HDL (mmol/L) | 1.05 ± 2.33 | 1.24 ± 0.49 | <0.001 | | LDL (mmol/L) | 2.70 ± 0.87 | 2.60 ± 0.69 | 0.135 | | hs-CRP (mmol/L) | 7.58 ± 9.46 | 2.33 ± 2.04 | <0.001 | | GLU (mmol/L) | 6.27 ± 2.51 | 5.46 ± 1.50 | <0.001 |
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CAD: coronary artery disease; BMI: body mass index; TG: triglycerides; TC: total cholesterol; HDL: high-density lipoprotein; LDL: low-density lipoprotein; Hs-CRP: high-sensitivity C-reactive protein; GLU: fasting blood-glucose.
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