Rs4612666 Polymorphism of the NLRP3 Gene Is Associated with the Occurrence of Large Artery Atherosclerotic Ischemic Strokes and Microembolic Signals

Table 6

Haplotype analysis of rs4612666-rs10754558-rs7512998 in LAA patients and control subjects.

haplotype	LAA group (freq)	Control group (freq)	value	OR	95% CI
C C C	26.52 (0.045)	44.38 (0.084)	0.009	0.521	0.317–0.856
C C T	98.42 (0.168)	95.45 (0.180)	0.620	0.924	0.677–1.262
C G C	7.81 (0.013)	15.02 (0.028)	-	-	-
C G T	156.24 (0.267)	160.15 (0.302)	0.205	0.844	0.649–1.097
T C C	11.15 (0.019)	0.08 (0.000)	-	-	-
T C T	163.91 (0.280)	133.09 (0.251)	0.254	1.169	0.894–1.529
T G C	3.52 (0.006)	2.51 (0.005)	-	-	-
T G T	118.42 (0.202)	79.31 (0.150)	0.019	1.453	1.062–1.988

All those frequencies < 0.03 were ignored in analysis.