Simvastatin Effects on Inflammation and Platelet Activation Markers in Hypercholesterolemia

Figure 1

Box-plot analysis of the endothelial dysfunction markers E-selectin and vascular endothelial growth factor (VEGF) in hypercholesterolemic patients assigned to diet alone (Control) or to diet plus simvastatin (Simva) at baseline (pre) and after a two-month follow-up (post). Significance of intragroup differences was estimated by paired t-test or Wilcoxon test, as appropriate. Solid lines: median values; boxes: interquartile range; whiskers: nonoutlier range; closed circles: outliers.