Simvastatin Effects on Inflammation and Platelet Activation Markers in Hypercholesterolemia

Figure 3

Box-plot analysis showing maximal aggregation to ADP, collagen, arachidonic acid (AA), and lysine acetylsalicylate (L-ASA) half-maximal inhibitory concentration (IC-50) in the presence of AA in hypercholesterolemic patients assigned to diet alone (Control) or to diet plus simvastatin (Simva) at baseline (pre) and after a two-month follow-up (post). Significance of intragroup differences was estimated by paired t-test or Wilcoxon test, as appropriate. Solid lines: median values; boxes: interquartile range; whiskers: nonoutlier range.