Prospects of Noncoding RNAs in Hepatocellular Carcinoma

Table 4

Potential role of snoRNA or their host genes in liver cancer.

SnoRNA/ their host genes	Potential role in liver cancer	Cells	References
SNORD113-1	A tumor suppressor role in HCC and a potential diagnostic and therapeutic target for HCC.	HepG2 and Huh7	[72]
SNHG3	Associated with malignant status and poor prognosis in HCC patients.	HCC	[73]
SNHG20	Up-regulated in patients with HCC, served as an independent prognostic predictor for HCC patients.	HCC and SK-Hep-1	[74, 75]
SNHG1	A prognostic biomarker and therapeutic target for HCC.	HCC and HepG2	[76, 77]
SNORD78	Associated with aggressive phenotype and poor prognosis of HCC	SK-Hep-1	[78]
SNHG6	Impacts HCC tumorigenesis by binding to up-frameshift protein 1 and regulating Smad7 expression.	HCC and L02	[79]
SNORD126	A therapeutic target	HepG2, LS174T and Huh7	[80]
SNHG12	A biomarker and a potential therapeutic target for HCC.	HCC	[81]
ACA11	A promising prognostic biomarker and therapeutic target for patients with HCC.	HCCLM9 and SK-Hep1	[82]
snoRA47	A valuable biomarker and a potential therapeutic target for HCC.	HCC	[83]
SNORD76	A promising prognostic biomarker in patients with HCC.	SK-Hep1 and Huh7	[84]