Rhodiola rosea Improves Lifespan, Locomotion, and Neurodegeneration in a Drosophila melanogaster Model of Huntington’s Disease

Figure 1

The effect of R. rosea on female D. melanogaster lifespan. (a) Compared to control-fed flies, HD, elav-Gal4, and UAS-HttQ93 flies showed a mean lifespan increase of 25%, 21%, and 17%, respectively. n=480, p<0.0001 for each strain, Log-Rank (Mantel-Cox) Test. (b) Analysis of the mean lifespan increases shows significant differences between the two treatments for elav-Gal4 and UAS-HttQ93 but not for HD flies. p<0.0001, ANOVA multiple comparisons test.

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(b)