Prognostic Significance of Blood Transfusion in Elderly Patients with Primary Diffuse Large B-Cell Lymphoma

Table 3

Multivariate analysis of prognostic factors for survival time in elderly patients with primary DLBCL.

Covariates	Overall survival				Progression-free survival
	Coefficient	SE	HR (95% CI)		Coefficient	SE	HR (95% CI)
B symptoms	N.A.	N.A.	N.A.	N.A.	−0.702	0.378	0.496 (0.236–1.040)	0.064
LDH	0.068	0.408	1.071 (0.482–2.380)	0.867	0.638	0.300	1.893 (1.052–3.405)	0.033
IPI	0.515	0.446	1.674 (0.698–4.014)	0.249	N.A.	N.A.	N.A.	N.A.
Cell of origin	1.348	0.494	3.848 (1.460–10.138)	0.006	0.428	0.337	1.534 (0.792–2.970)	0.204
Albumin	−0.568	0.376	0.567 (0.271–1.184)	0.131	N.A.	N.A.	N.A.	N.A.
Rituximab	0.922	0.367	2.515 (1.225–5.167)	0.012	N.A.	N.A.	N.A.	N.A.
Blood transfusion	−0.327	0.424	0.721 (0.314–1.654)	0.440	−0.654	0.318	0.520 (0.279–0.970)	0.040

LDH: lactate dehydrogenase; IPI: International Prognostic Index; Hb: hemoglobin; Alb: albumin; SE: standard error; HR: hazard ratio; CI: confidence interval; N.A.: not available.