Effective Treatment of Chronic Proliferative Cholangitis by Local Gentamicin Infusion in Rabbits

Figure 1

Pathological changes of the common bile duct wall. Hematoxylin-eosin (HE) staining of the common bile duct (original magnification ×50) showed the hyperplasia of epithelium and submucosal glands of the bile duct wall in positive control group (a) and the hyperplasia was inhibited by gentamicin in antibiotic treatment group (b), compared with those in sham-operation group (c). The thickness of the bile duct wall was measured (d) and a significant difference was shown between positive control and antibiotic treatment group. (Positive control versus antibiotic treatment group; antibiotic treatment vs. sham-operation group, p<0.001.)

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