Self-Nanoemulsifying Drug Delivery System of Tetrandrine for Improved Bioavailability: Physicochemical Characterization and Pharmacokinetic Study

Figure 2

Pseudo-ternary phase diagram consisting of oleic acid, the mixture of surfactant (SPC/cremophor RH-40, 1 : 2), and PEG₄₀₀ with surfactant/cosurfactant ratios of (a) 1 : 1, (b) 3 : 2, (c) 2 : 1, and (d) 3 : 1. The blank region represents oil/water microemulsion formation area.

(a)

(b)

(c)

(d)